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14章 制吐剤

三好寛二、堤保夫 「14.1 総論」 Page 328-333, 2023

城戸健士郎、三好寛二 「14.2 ドパミンD2受容体拮抗薬」 Page 334-337, 2023

里見志帆、三好寛二 「14.3 5-HT3受容体拮抗薬」 Page 338-341, 2023

三好寛二、堤保夫 「14.4 ステロイド」 Page 342-345, 2023


Toyota Y, Kondo T, Shorin D, Sumii A, Kido K, Watanabe T, Otsuki S, Kanzaki R, Miyoshi H, Yasuda T, Horikawa YT, Mukaida K, Tsutsumi YM. Rapid dantrolene administration with body temperature monitoring is associated with decreased mortality in Japanese malignant hyperthermia events. BioMed Res Int 8340209, 2023.


Sumii A, Miyoshi H, Kato T, Otsuki S, Horikawa YT, Satomi S, Saeki N, Tsutsumi YM. Perioperative Management of Recurrent Hemophagocytic Syndrome in a Pregnant Woman: A Case Report. Am J Case Rep 24: e939369, 2023.


Suga H,Miyoshi H, Arata K, Sumii A, Watanabe T, Kido K, Otsuki S Tsutsumi YM.Anesthetic management of cesarean section in COVID-19-positive pregnant women in Japan: Three case reports and review of the literature. Hiroshima J Med Sci 72: 21-25, 2023


Narasaki S, Noguchi S, Urabe T, Harada K, Hide I, Tanaka S, Yanase Y, Kajimoto T, Uchida K, Tsutsumi YM, Sakai N. Identification of protein kinase C domains involved in its translocation induced by propofol. Eur J Pharmacol 955: 175806, 2023.


Matsumoto A, Satomi S, Kakuta N, Narasaki S, Toyota Y, Miyoshi H, Horikawa YT, Saeki N, Tanaka K, and Tsutsumi YM. Remimazolam’s effects on postoperative nausea and vomiting are similar to those of propofol after laparoscopic gynecological surgery: a randomized controlled trial. J Clin Med 12: 5402, 2023.


Kato T, Kamiya S, Narasaki S, Sumii A, Tsutsumi YM, Machida K, Hara K, Izumi-Mishima Y, Tsutsumi R, and Sakaue H. Partially hydrolyzed guar gum intake supports the gut microbiota and attenuates inflammation during influenza H1N1 virus infection in mice. Nutrients 15: 4252, 2023


Miyoshi H, Otsuki S, Mukaida K, Kido K, Sumii A, Ikeda T, Noda Y, Yasuda T, Narasaki S, Kato T, Kamiya S, Horikawa YT, Tsutsumi YM. Effects of remimazolam on intracellular calcium dynamics in myotubes derived from patients with malignant hyperthermia and functional analysis of type 1 ryanodine receptor gene variants. Genes 14: 2009, 2023.


Noguchi S, Kajimoto T, Kumamoto T, Shingai M, Narasaki S, Urabe T, Imamura S, Harada K, Hide I, Tanaka S, Yanase Y, Nakamura SI, Tsutsumi YM, and Sakai N. Features and mechanisms of propofol-induced protein kinase C (PKC) translocation and activation in living cells. Front Pharmacol 14: 12884586, 2023.


Toyota Y, Kondo T, Oshita K, Haraki T, Narasaki S, Kido K, Kamiya S, Nakamura R, Saeki N, Horikawa YT, and Tsutsumi YM. Remimazolam-based anesthesia with flumazenil allows faster emergence than propofol-based anesthesia in older patients undergoing spinal surgery: A randomized controlled trial. Medicine 102: 46, 2023.


Shimizu Y, Ohshimo S, Saeki N, Oue K, Sasaki U, Imamura S, Kamio H, Imado E, Sadamori T, Tsutsumi YM, and Shime N. New acoustic monitoring system quantifying aspiration risk during monitored anaesthesia care. Sci Rep 13: 20196, 2023.


Shorin D, Kamiya S, Nakamura R, Ishibashi A, Saeki N, Tsuji T, and Tsutsumi YM. Prediction of blood pressure changes during surgical incision using minimum evoked current of vascular stiffness value under sevoflurane anesthesia. Sci Rep 13: 20486, 2023.


Ishii T, Miyoshi H, Kubo T, Tsutsumi YM, Horikawa YT, and Tanaka H. Delayed nonimmune anaphylaxis caused by ropivacaine for preoperative nerve blocks: a case report. A&A Practice 17: e01727, 2023.


Shimizu Y, Saeki N, Ohshimo S, Doi M, Oue K, Yoshida M, Takahashi T, Oda A, Sadamori T, Tsutsumi YM, and Shime N. Usefulness of new acoustic respiratory sound monitoring with artificial intelligence for upper airway assessment in obese patients during monitored anesthesia care. J Med Invest 70: 430-435, 2023.


三好寛二、堤保夫「悪性高熱症の診断と課題」『臨床麻酔』47: 21-27, 2023


森脇克行、平松咲子、新友里、木野下冨士子、河野浩和、堤保夫「手術室薬剤の投薬安全とセキュリティー:周術期管理チームのための基礎知識」『麻酔』72: 318-329, 2023.


森脇克行、中村隆治、堤保夫「新しいICD-11慢性疼痛コードの臨床応用」『産科と婦人科』59: 627-633, 2023.


梅田絢子、田口志麻、仁井内浩、池尻佑美、中村隆治、堤保夫「院内情報共有体制構築の契機となった静脈路確保による新規の複合性局所疼痛症候群 (CRPS) の1例」『日本ペインクリニック学会誌』30: 199-202, 2023.


科学研究費 基盤研究(C) 2023年度~2025年度 課題番号:23K08332





科学研究費 基盤研究(C) 2023年度~2027年度 課題番号:23K08409





科学研究費 基盤研究(C) 2023年度~2025年度 課題番号:23K08361





科学研究費 基盤研究(C) 2023年度~2025年度 課題番号:23K08382





科学研究費 若手研究 2023年度~2024年度 課題番号:23K15598





令和5年度医療研究開発推進事業費補助金(橋渡し研究プログラム) 2023年度 課題番号:A555





中冨健康科学振興財団 令和5年度(第36回)研究助成金






2023.3.23 博士(医学) 甲第9254号 渡辺知幸

学位論文:Effects of remimazolam and propofol on Ca2+ regulation by ryanodine receptor 1 with malignant hyperthermia mutation. Biomed Res Int 8845129, 2021.


2023.9.20 博士(医学) 甲第9351号 楢崎壮志

学位論文:Identification of protein kinase C domains involved in its translocation induced by propofol. Eur J Pharmacol 955: 175806, 2023.